neurological disease — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1856	Colivelin		Beta Amyloid , STAT
	Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).		Beta Amyloid , STAT
T9989	AChE-IN-27		Others
	AChE-IN-27 is a small molecule used for high-throughput assays.		Others
T1476	Pramipexole	SND 919	Dopamine Receptor
	Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not...		Dopamine Receptor
T1594	Vecuronium bromide	ORG NC 45	AChR
	Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity.		AChR
T7805	GW791343 dihydrochloride	GW791343 (HCl)	P2X Receptor
	GW791343 dihydrochloride (GW791343 (HCl)) is a P2X7 allosteric modulator.		P2X Receptor
T3198L	PRE-084 hydrochloride		Sigma receptor
	PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).		Sigma receptor
T3217	PF-CBP1 hydrochloride	PF-CBP1 HCl	Epigenetic Reader Domain , Histone Acetyltransferase
	PF-CBP1 hydrochloride (PF-CBP1 HCl) is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively.		Epigenetic Reader Domain , Histone Acetyltransferase
T4497	Amifampridine	3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine	Others
	Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ...		Others
T6951	Pramipexole dihydrochloride hydrate	Pramipexole 2HCl Monohydrate,Mirapex	Dopamine Receptor
	Pramipexole dihydrochloride hydrate (Mirapex) is the hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors in the striatum and su...		Dopamine Receptor
T35878	N-(3-Aminopropyl)cyclohexylamine		Others
	N-(3-Aminopropyl)cyclohexylamine, a derivative of cyclohexylamine, functions as a selective and competitive inhibitor of spermine synthase, making it suitable for research on neurological diseases[1].		Others
T1045	Trimipramine maleate	Surmontil maleate	Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor
	Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal...
T6526	GW791343 trihydrochloride	GW791343 3HCl	P2X Receptor
	GW791343 trihydrochloride (GW791343 3HCl) is aHCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7.		P2X Receptor
T27143	Delucemine Hydrochloride	NPS 1506,Delucemine,Delucemine HCl,NPS1506,NPS-1506	NMDAR
	Delucemine Hydrochloride (Delucemine) is a polyamine NMDA receptor antagonist used in the study of neurological disorders such as depression and Alzheimer's disease.		NMDAR
T28441	PPI-1019	PPI1019,Apan	Beta Amyloid
	PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).		Beta Amyloid
T31079	CP-810123	CP 810123,UNII-E6G4550EC4,CP810123	AChR
	CP-810123 is a new alpha 7 nAChR agonist for the treatment of cognitive impairment associated with psychiatric or neurological disorders such as schizophrenia and Alzheimer's disease.		AChR
TP1195	Cibinetide	ARA290	Others
	Cibinetide (ARA290) is a nonerythropoietic peptide engineered from erythropoietin,, and used for neurological disease treatment.		Others
T13047	Synta66		Calcium Channel
	Synta66 is a store-operated calcium entry channel Orai inhibitor, and used for the research of neurological disease.		Calcium Channel
T64344	N-Methyl-DL-aspartic acid		NMDAR
	N-Methyl-DL-aspartic acid, a glutamate analogue and NMDA receptor agonist, is utilized in neurological disease research.		NMDAR
TP1866L	β-amyloid 1-11 acetate(190436-05-6 free base)		Beta Amyloid
	β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.		Beta Amyloid
T11949	Masupirdine mesylate	SUVN-502 mesylate,SVN-502 mesylate	5-HT Receptor
	Masupirdine mesylate (SUVN-502 mesylate) is a selective 5-HT6 receptor antagonist that crosses the blood-brain barrier.Masupirdine mesylate is used in the study of neurological disorders such as Alzheimer's disease and d...		5-HT Receptor